Umblical infection
Infection  cause

1. Poor care of biblical cord 
2. Poor hygiene
3. Umblical cord is contaminated the time of cutting after delivery

Organism

1. Staphylococcus aureus
2. streptococcus

Sign and Symptoms

1. Redness
2. Pus discharge
3. Fever

Management

1. GV paint  (gentian violet)
2. Antibiotic 

   Ampi+cloxa :50mg/kg/dose  

    Cefotaxime

Dosing & Uses

Pediatric

Dosing Forms & Strengths

Susceptible Infections

<12 years old or < 50 kg: 50-200 mg/kg/day IV/IM divided q6-8hr 

>12 years old or >50 kg: As in adults

Epiglotitis

<12 years old or < 50 kg: 150-200 mg/kg/day IV/IM divided QID with clindamycin for 7-10 days 

>12 years old or >50 kg: As in adults

Meningitis

<12 years old or < 50 kg: 200 mg/kg/day IV/IM divided q6hr 

>12 years old or >50 kg: As in adults

Pneumonia

<12 years old or < 50 kg: 200 mg/kg/day IV divided q8hr 

>12 years old or >50 kg: As in adults

Sepsis

<12 years old or < 50 kg: 150 mg/kg/day IV divided q8hr 

>12 years old or >50 kg: As in adults

Typhoid Fever

<12 years old or < 50 kg: 150-200 mg/kg/day IV/IM divided TID/QID; 12 g/day maximum 

Fluoroquinolone resistant: 80 mg/kg/day IV/IM divided TID/QID; 12 g/day maximum

>12 years old or >50 kg: As in adults

General Cefotaxime Dosing

0-1 week: 50 mg/kg IV q12hr 

1-4 weeks: 50 mg/kg IV q8hr

1 month old to 12 years old or <50 kg: 50-180 mg/kg/day IV divided q4-6hr

Meningitis: 200 mg/kg/day divided q6hr IV/IM

Dosing & Uses

Adult

Dosing Forms & Strengths

Gonococcal Urethritis/Cervicitis

0.5 g IM (single dose)

Gonorrhea, Rectal (Men)

1 g IM (single dose)

Gonorrhea, Rectal (Women)

0.5 g IM (single dose)

Moderate to Severe Infections

1 to 2 g IV/IM q8hr

More Severe Infections (Septicemia)

2 g IV q6-8hr

Life-Threatening Infections

2 g IV q4hr up to 12 g/day

Perioperative Prophylaxis

Single 1 g IM or IV dose administered 30 to 90 minutes prior to start of surgery

Uncomplicated Infections

1 g IV/IM q12h

Refer to surgical management  of higher centre